{"version": "1.0", "type": "rich", "title": "Huh. Hearing that the \"antivirals\" they give the immunosuppressed re:Covid work by inducing genetic mutation, and while this...", "author_name": "kontextmaschine", "author_url": "https://kontextmaschine.com", "provider_name": "kontextmaschine", "provider_url": "https://kontextmaschine.com", "url": "https://kontextmaschine.com/post/704483613227499520/", "html": "<p><a class=\"tumblr_blog\" href=\"https://manyblinkinglights.tumblr.com/post/704483099233353728/yeah-molnupiravir-or-something-sic-im-not\" target=\"_blank\">manyblinkinglights</a>:</p><blockquote><p><a class=\"tumblr_blog\" href=\"https://www.tumblr.com/blog/view/poipoipoi-2016/704481353947873280\" target=\"_blank\">poipoipoi-2016</a>:</p><blockquote><p><a class=\"tumblr_blog\" href=\"/post/704481097138978816/\" target=\"_blank\">kontextmaschine</a>:</p><blockquote><p>Huh. Hearing that the &ldquo;antivirals&rdquo; they give the immunosuppressed re:Covid work by inducing genetic mutation, and while this usually results in non-viable virus code (that&rsquo;s the mechanism, after all) some fraction is highly mutated but still viable, some fraction of <i>that</i> fraction is in fact <i>more</i> viable than the parent strain, and applied across a whole-humanity disease that <b>already</b> has such a high &ldquo;R&rdquo; of new infections seeded per established case the effect is to accelerate its evolution</p></blockquote><p>IIRC, this was the one that started with M and not Paxlovid.  </p><p>Also yes, that was noticed at the time along with drastically reduced efficacy over Paxlovid and while that&rsquo;s been its own thing (Kill a puppy to a get a 10/15-dose course IMO.  5 isn&rsquo;t long enough), I&rsquo;d take the Paxlovid thing over the mutation thing.  </p></blockquote><p>Yeah, molnupiravir or something (sic, I\u2019m not looking it up). My med twitter mutual was bitching up a storm about it today. It doesn\u2019t do anything but up your cancer risk and hypermutate the coronavirus, etc.</p></blockquote>\n<p>Yeah, that&rsquo;s it. Okay, this was re: a drug in <i>testing</i>, worrier Twitter combines apocalypticism with grounded biomedical understanding in a way that&rsquo;s hard to tease apart sometimes. </p>"}